Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage

Adult stem cells and tumor-initiating cells (TICs) often employ different mechanisms of DNA damage response (DDR) as compared to other tissue cell types. However, little is known about how mammary stem cells (MaSCs) and mammary TICs respond to DNA damage. Using the mouse mammary gland and syngeneic...

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Detalles Bibliográficos
Autores principales: Chang, Chi-Hsuan, Zhang, Mei, Rajapakshe, Kimal, Coarfa, Cristian, Edwards, Dean, Huang, Shixia, Rosen, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618454/
https://www.ncbi.nlm.nih.gov/pubmed/26300228
http://dx.doi.org/10.1016/j.stemcr.2015.07.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618454/
https://www.ncbi.nlm.nih.gov/pubmed/26300228
http://dx.doi.org/10.1016/j.stemcr.2015.07.009

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