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Transcriptional Derepression Uncovers Cryptic Higher-Order Genetic Interactions

Disruption of certain genes can reveal cryptic genetic variants that do not typically show phenotypic effects. Because this phenomenon, which is referred to as ‘phenotypic capacitance’, is a potential source of trait variation and disease risk, it is important to understand how it arises at the gene...

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Detalles Bibliográficos
Autores principales: Taylor, Matthew B., Ehrenreich, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618523/
https://www.ncbi.nlm.nih.gov/pubmed/26484664
http://dx.doi.org/10.1371/journal.pgen.1005606