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The LRR receptor Islr2 is required for retinal axon routing at the vertebrate optic chiasm

BACKGROUND: In the visual system of most binocular vertebrates, the axons of retinal ganglion cells (RGCs) diverge at the diencephalic midline and extend to targets on both ipsi- and contralateral sides of the brain. While a molecular mechanism explaining ipsilateral guidance decisions has been char...

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Detalles Bibliográficos
Autores principales: Panza, Paolo, Sitko, Austen A., Maischein, Hans-Martin, Koch, Iris, Flötenmeyer, Matthias, Wright, Gavin J., Mandai, Kenji, Mason, Carol A., Söllner, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618557/
https://www.ncbi.nlm.nih.gov/pubmed/26492970
http://dx.doi.org/10.1186/s13064-015-0050-x