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Basic Fibroblast Growth Factor-Mediated Overexpression of Vascular Endothelial Growth Factor in 1F6 Human Melanoma Cells is Regulated by Activation of PI-3K and p38 MAPK

Background: 1F6 human melanoma xenografts overexpressing either the 18 kD (18kD) form or all (ALL) forms of human basic fibroblast growth factor (bFGF) demonstrate an abundant number of microvessels and accelerated growth. We now examined whether bFGF mediates vascular endothelial growth factor (VEG...

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Detalles Bibliográficos
Autores principales: Fontijn, Dennis, Bosch, Linda J. W., Duyndam, Monique C. A., van Berkel, Maria P. A., Janmaat, Maarten L., Boven, Epie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618591/
https://www.ncbi.nlm.nih.gov/pubmed/19478386
http://dx.doi.org/10.3233/CLO-2009-0477