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Global loss of a nuclear lamina component, lamin A/C, and LINC complex components SUN1, SUN2, and nesprin-2 in breast cancer

Cancer cells exhibit a variety of features indicative of atypical nuclei. However, the molecular mechanisms underlying these phenomena remain to be elucidated. The linker of nucleoskeleton and cytoskeleton (LINC) complex, a nuclear envelope protein complex consisting mainly of the SUN and nesprin pr...

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Detalles Bibliográficos
Autores principales: Matsumoto, Ayaka, Hieda, Miki, Yokoyama, Yuhki, Nishioka, Yu, Yoshidome, Katsuhide, Tsujimoto, Masahiko, Matsuura, Nariaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618625/
https://www.ncbi.nlm.nih.gov/pubmed/26175118
http://dx.doi.org/10.1002/cam4.495