Applicability of second-generation upcyte® human hepatocytes for use in CYP inhibition and induction studies

Human upcyte® hepatocytes are proliferating hepatocytes that retain many characteristics of primary human hepatocytes. We conducted a comprehensive evaluation of the application of second-generation upcyte® hepatocytes from four donors for inhibition and induction assays using a selection of referen...

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Detalles Bibliográficos
Autores principales: Ramachandran, Sarada D, Vivarès, Aurélie, Klieber, Sylvie, Hewitt, Nicola J, Muenst, Bernhard, Heinz, Stefan, Walles, Heike, Braspenning, Joris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618636/
https://www.ncbi.nlm.nih.gov/pubmed/26516577
http://dx.doi.org/10.1002/prp2.161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618636/
https://www.ncbi.nlm.nih.gov/pubmed/26516577
http://dx.doi.org/10.1002/prp2.161

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