Interrogating the relationship between rat in vivo tissue distribution and drug property data for >200 structurally unrelated molecules

The ability to explain distribution patterns from drug physicochemical properties and binding characteristics has been explored for more than 200 compounds by interrogating data from quantitative whole body autoradiography studies (QWBA). These in vivo outcomes have been compared to in silico and in...

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Detalles Bibliográficos
Autores principales: Harrell, Andrew W, Sychterz, Caroline, Ho, May Y, Weber, Andrew, Valko, Klara, Negash, Kitaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618644/
https://www.ncbi.nlm.nih.gov/pubmed/26516585
http://dx.doi.org/10.1002/prp2.173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618644/
https://www.ncbi.nlm.nih.gov/pubmed/26516585
http://dx.doi.org/10.1002/prp2.173

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