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Preferential Propagation of Competent SIX2+ Nephronic Progenitors by LIF/ROCKi Treatment of the Metanephric Mesenchyme

Understanding the mechanisms responsible for nephrogenic stem cell preservation and commitment is fundamental to harnessing the potential of the metanephric mesenchyme (MM) for nephron regeneration. Accordingly, we established a culture model that preferentially expands the MM SIX2+ progenitor pool...

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Detalles Bibliográficos
Autores principales: Tanigawa, Shunsuke, Sharma, Nirmala, Hall, Michael D., Nishinakamura, Ryuichi, Perantoni, Alan O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618653/
https://www.ncbi.nlm.nih.gov/pubmed/26321142
http://dx.doi.org/10.1016/j.stemcr.2015.07.015