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Transcriptional Profiling of Hypoxic Neural Stem Cells Identifies Calcineurin-NFATc4 Signaling as a Major Regulator of Neural Stem Cell Biology

Neural stem cells (NSCs) reside in a hypoxic microenvironment within the brain. However, the crucial transcription factors (TFs) that regulate NSC biology under physiologic hypoxia are poorly understood. Here we have performed gene set enrichment analysis (GSEA) of microarray datasets from hypoxic v...

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Detalles Bibliográficos
Autores principales: Moreno, Marta, Fernández, Virginia, Monllau, Josep M., Borrell, Víctor, Lerin, Carles, de la Iglesia, Núria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618660/
https://www.ncbi.nlm.nih.gov/pubmed/26235896
http://dx.doi.org/10.1016/j.stemcr.2015.06.008