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α-5 Laminin Synthesized by Human Pluripotent Stem Cells Promotes Self-Renewal

Substrate composition significantly impacts human pluripotent stem cell (hPSC) self-renewal and differentiation, but relatively little is known about the role of endogenously produced extracellular matrix (ECM) components in regulating hPSC fates. Here we identify α-5 laminin as a signature ECM comp...

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Detalles Bibliográficos
Autores principales: Laperle, Alex, Hsiao, Cheston, Lampe, Michael, Mortier, Jaime, Saha, Krishanu, Palecek, Sean P., Masters, Kristyn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618661/
https://www.ncbi.nlm.nih.gov/pubmed/26235893
http://dx.doi.org/10.1016/j.stemcr.2015.06.009