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α-5 Laminin Synthesized by Human Pluripotent Stem Cells Promotes Self-Renewal
Substrate composition significantly impacts human pluripotent stem cell (hPSC) self-renewal and differentiation, but relatively little is known about the role of endogenously produced extracellular matrix (ECM) components in regulating hPSC fates. Here we identify α-5 laminin as a signature ECM comp...
Autores principales: | Laperle, Alex, Hsiao, Cheston, Lampe, Michael, Mortier, Jaime, Saha, Krishanu, Palecek, Sean P., Masters, Kristyn S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618661/ https://www.ncbi.nlm.nih.gov/pubmed/26235893 http://dx.doi.org/10.1016/j.stemcr.2015.06.009 |
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