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Unconserved C terminal of human cytomegalovirus tegument protein pUL76 elicits nuclear aggresome formation and induces DNA damage in transfected cells

BACKGROUND: The HCMV UL76 gene is a member of UL24 family in herpes virus and encodes a highly conserved herpes virus protein. Inherited from common ancestor, members of Herpes(_)UL24 family encode proteins with a conserved N terminal and varied in C terminal region. To define which region (conserve...

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Detalles Bibliográficos
Autores principales: Zhang, Wenchang, Yao, Yao, Chen, Jingxian, Wang, Mingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618751/
https://www.ncbi.nlm.nih.gov/pubmed/26494186
http://dx.doi.org/10.1186/s12929-015-0205-4