Cargando…

Unconserved C terminal of human cytomegalovirus tegument protein pUL76 elicits nuclear aggresome formation and induces DNA damage in transfected cells

BACKGROUND: The HCMV UL76 gene is a member of UL24 family in herpes virus and encodes a highly conserved herpes virus protein. Inherited from common ancestor, members of Herpes(_)UL24 family encode proteins with a conserved N terminal and varied in C terminal region. To define which region (conserve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Wenchang, Yao, Yao, Chen, Jingxian, Wang, Mingli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618751/ https://www.ncbi.nlm.nih.gov/pubmed/26494186 http://dx.doi.org/10.1186/s12929-015-0205-4

Ejemplares similares

Human Cytomegalovirus Tegument Protein pUL71 Is Required for Efficient Virion Egress
por: Womack, Andrew, et al.
Publicado: (2010)

Dual Function of the pUL7-pUL51 Tegument Protein Complex in Herpes Simplex Virus 1 Infection
por: Albecka, Anna, et al.
Publicado: (2017)

The pUL37 tegument protein guides alpha-herpesvirus retrograde axonal transport to promote neuroinvasion
por: Richards, Alexsia L., et al.
Publicado: (2017)

New Insights into Human Cytomegalovirus pUL52 Structure
por: Muller, Clotilde, et al.
Publicado: (2021)

The Large Tegument Protein pUL36 Is Essential for Formation of the Capsid Vertex-Specific Component at the Capsid-Tegument Interface of Herpes Simplex Virus 1
por: Fan, Wan H., et al.
Publicado: (2014)

The herpes simplex virus tegument protein pUL21 is required for viral genome retention within capsids
por: Thomas, Ethan C. M., et al.
Publicado: (2022)

Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex
por: Butt, Benjamin G, et al.
Publicado: (2020)

The Cytomegalovirus protein pUL37×1 targets mitochondria to mediate neuroprotection
por: Hong, Chien Tai, et al.
Publicado: (2016)

The contribution of pUL74 to growth of human cytomegalovirus is masked in the presence of RL13 and UL128 expression
por: Laib Sampaio, Kerstin, et al.
Publicado: (2016)

The Cyclin-Dependent Kinase Ortholog pUL97 of Human Cytomegalovirus Interacts with Cyclins
por: Graf, Laura, et al.
Publicado: (2013)

The Complex Regulatory Role of Cytomegalovirus Nuclear Egress Protein pUL50 in the Production of Infectious Virus
por: Häge, Sigrun, et al.
Publicado: (2021)

Identification of a short sequence in the HCMV terminase pUL56 essential for interaction with pUL89 subunit
por: Ligat, G., et al.
Publicado: (2017)

N-Linked Glycosylation and Expression of Duck Plague Virus pUL10 Promoted by pUL49.5
por: Li, Chunmei, et al.
Publicado: (2023)

Human cytomegalovirus UL76 induces chromosome aberrations
por: Siew, Voon-Kwan, et al.
Publicado: (2009)

Human cytomegalovirus protein pUL36: A dual cell death pathway inhibitor
por: Fletcher-Etherington, Alice, et al.
Publicado: (2020)

Human Cytomegalovirus Nuclear Capsids Associate with the Core Nuclear Egress Complex and the Viral Protein Kinase pUL97
por: Milbradt, Jens, et al.
Publicado: (2018)

Inner tegument protein pUL37 of herpes simplex virus type 1 is involved in directing capsids to the trans-Golgi network for envelopment
por: Pasdeloup, David, et al.
Publicado: (2010)

The Human Cytomegalovirus UL76 Gene Regulates the Level of Expression of the UL77 Gene
por: Isomura, Hiroki, et al.
Publicado: (2010)

Phenotypical Characterization of the Nuclear Egress of Recombinant Cytomegaloviruses Reveals Defective Replication upon ORF-UL50 Deletion but Not pUL50 Phosphosite Mutation
por: Häge, Sigrun, et al.
Publicado: (2021)

Functional Domains of the Herpes Simplex Virus Type 1 Tegument Protein pUL37: The Amino Terminus is Dispensable for Virus Replication in Tissue Culture
por: Grzesik, Peter, et al.
Publicado: (2019)

Human Cytomegalovirus pUL79 Is an Elongation Factor of RNA Polymerase II for Viral Gene Transcription
por: Perng, Yi-Chieh, et al.
Publicado: (2014)

The Cytomegalovirus Protein Kinase pUL97: Host Interactions, Regulatory Mechanisms and Antiviral Drug Targeting
por: Steingruber, Mirjam, et al.
Publicado: (2020)

8‐Hydroxy‐1,6‐naphthyridine‐7‐carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease
por: Jung, Eunkyung, et al.
Publicado: (2022)

Recombinant Human Cytomegalovirus Expressing an Analog-Sensitive Kinase pUL97 as Novel Tool for Functional Analyses
por: Krämer, Nadine, et al.
Publicado: (2022)

Identification of Small Molecule Inhibitors of Human Cytomegalovirus pUL89 Endonuclease Using Integrated Computational Approaches
por: Almehmadi, Mazen, et al.
Publicado: (2023)

The Cytomegalovirus Tegument Protein UL35 Antagonizes Pattern Recognition Receptor-Mediated Type I IFN Transcription
por: Fabits, Markus, et al.
Publicado: (2020)

Distribution of the CMV glycoprotein gH/gL/gO and gH/gL/pUL128/pUL130/pUL131A complex variants and associated clinical manifestations in infants infected congenitally or postnatally
por: Paradowska, Edyta, et al.
Publicado: (2019)

Human Cytomegalovirus Protein pUL117 Targets the Mini-Chromosome Maintenance Complex and Suppresses Cellular DNA Synthesis
por: Qian, Zhikang, et al.
Publicado: (2010)

Human Cytomegalovirus-Encoded pUL7 Is a Novel CEACAM1-Like Molecule Responsible for Promotion of Angiogenesis
por: MacManiman, Jason D., et al.
Publicado: (2014)

The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain
por: Steingruber, Mirjam, et al.
Publicado: (2015)

The human cytomegalovirus glycoprotein pUL11 acts via CD45 to induce T cell IL-10 secretion
por: Zischke, Jasmin, et al.
Publicado: (2017)

Functional Relevance of the Interaction between Human Cyclins and the Cytomegalovirus-Encoded CDK-Like Protein Kinase pUL97
por: Schütz, Martin, et al.
Publicado: (2021)

Cyclin A Degradation by Primate Cytomegalovirus Protein pUL21a Counters Its Innate Restriction of Virus Replication
por: Caffarelli, Nicolas, et al.
Publicado: (2013)

Proteomic Interaction Patterns between Human Cyclins, the Cyclin-Dependent Kinase Ortholog pUL97 and Additional Cytomegalovirus Proteins
por: Steingruber, Mirjam, et al.
Publicado: (2016)

Full-length human cytomegalovirus terminase pUL89 adopts a two-domain structure specific for DNA packaging
por: Theiß, Janine, et al.
Publicado: (2019)

Human cytomegalovirus pUL97 upregulates SOCS3 expression via transcription factor RFX7 in neural progenitor cells
por: Wang, Xian-Zhang, et al.
Publicado: (2023)

Expression and intracellular localization of duck enteritis virus pUL38 protein
por: Xiang, Jun, et al.
Publicado: (2010)

Duck enteritis virus UL21 is a late gene encoding a protein that interacts with pUL16
por: Yang, Linjiang, et al.
Publicado: (2020)

Human Cytomegalovirus pUL11, a CD45 Ligand, Disrupts CD4 T Cell Control of Viral Spread in Epithelial Cells
por: Osanyinlusi, Samuel A., et al.
Publicado: (2022)

The Herpes Simplex Virus Protein pUL31 Escorts Nucleocapsids to Sites of Nuclear Egress, a Process Coordinated by Its N-Terminal Domain
por: Funk, Christina, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_5l80n6c6i4fedeq5ntivktb7p8