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Tegaserod mimics the neurostimulatory glycan polysialic acid and promotes nervous system repair

Glycans attached to the cell surface via proteins or lipids or exposed in the extracellular matrix affect many cellular processes, including neuritogenesis, cell survival and migration, as well as synaptic activity and plasticity. These functions make glycans attractive molecules for stimulating rep...

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Detalles Bibliográficos
Autores principales: Bushman, J., Mishra, B., Ezra, M., Gul, S., Schulze, C., Chaudhury, S., Ripoll, D., Wallqvist, A., Kohn, J., Schachner, M., Loers, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618794/
https://www.ncbi.nlm.nih.gov/pubmed/24067923
http://dx.doi.org/10.1016/j.neuropharm.2013.09.014