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High Resolution Comparative Genomic Hybridization Detects 7–8 Megabasepair Deletion in PCR Amplified DNA(1)

We investigated if any change in spatial resolution of comparative genomic hybridization analysis could be detected when using DNA amplified by degenerate oligonucleotide primed PCR (DOP‐PCR) as opposed to the use of unamplified DNA. Five DNA samples from B‐cell leukemias with small 11q deletions we...

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Detalles Bibliográficos
Autores principales: Larsen, Jacob, Ottesen, Anne Marie, Kirchhoff, Maria, Lundsteen, Claes, Larsen, Jørgen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618809/
https://www.ncbi.nlm.nih.gov/pubmed/11904461
http://dx.doi.org/10.1155/2001/301570