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Ligands of the Mitochondrial 18 kDa Translocator Protein Attenuate Apoptosis of Human Glioblastoma Cells Exposed to Erucylphosphohomocholine

Background: We have previously shown that the anti-neoplastic agent erucylphosphohomocholine (ErPC3) requires the mitochondrial 18 kDa Translocator protein (TSPO), formerly known as the peripheral-type benzodiazepine receptor (PBR), to induce cell death via the mitochondrial apoptosis pathway. Metho...

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Detalles Bibliográficos
Autores principales: Kugler, Wilfried, Veenman, Leo, Shandalov, Yulia, Leschiner, Svetlana, Spanier, Ilana, Lakomek, Max, Gavish, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618834/
https://www.ncbi.nlm.nih.gov/pubmed/18791274
http://dx.doi.org/10.3233/CLO-2008-0431