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Lactobacillus plantarum displaying CCL3 chemokine in fusion with HIV-1 Gag derived antigen causes increased recruitment of T cells

BACKGROUND: Chemokines are attractive candidates for vaccine adjuvants due to their ability to recruit the immune cells. Lactic acid bacteria (LAB)-based delivery vehicles have potential to be used as a cheap and safe option for vaccination. Chemokine produced on the surface of LAB may potentially e...

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Detalles Bibliográficos
Autores principales: Kuczkowska, Katarzyna, Mathiesen, Geir, Eijsink, Vincent G. H., Øynebråten, Inger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618854/
https://www.ncbi.nlm.nih.gov/pubmed/26494531
http://dx.doi.org/10.1186/s12934-015-0360-z