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Free exopolysaccharide from Mycoplasma mycoides subsp. mycoides possesses anti-inflammatory properties

In this study we explored the immunomodulatory properties of highly purified free galactan, the soluble exopolysaccharide secreted by Mycoplasma mycoides subsp. mycoides (Mmm). Galactan was shown to bind to TLR2 but not TLR4 using HEK293 reporter cells and to induce the production of the anti-inflam...

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Detalles Bibliográficos
Autores principales: Totté, Philippe, Puech, Carinne, Rodrigues, Valérie, Bertin, Clothilde, Manso-Silvan, Lucia, Thiaucourt, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618858/
https://www.ncbi.nlm.nih.gov/pubmed/26490663
http://dx.doi.org/10.1186/s13567-015-0252-6