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Soluble epoxide hydrolase inhibitor enhances synaptic neurotransmission and plasticity in mouse prefrontal cortex

BACKGROUND: The soluble epoxide hydrolase (sEH) is an important enzyme chiefly involved in the metabolism of fatty acid signaling molecules termed epoxyeicosatrienoic acids (EETs). sEH inhibition (sEHI) has proven to be protective against experimental cerebral ischemia, and it is emerging as a thera...

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Detalles Bibliográficos
Autores principales: Wu, Han-Fang, Yen, Hsin-Ju, Huang, Chi-Chen, Lee, Yi-Chao, Wu, Su-Zhen, Lee, Tzong-Shyuan, Lin, Hui-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618874/
https://www.ncbi.nlm.nih.gov/pubmed/26494028
http://dx.doi.org/10.1186/s12929-015-0202-7