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Estrogen Receptor (ER)-α36 Is Involved in Estrogen- and Tamoxifen-Induced Neuroprotective Effects in Ischemic Stroke Models

The neuroprotection by estrogen (E2) and tamoxifen is well documented in experimental stroke models; however, the exact mechanism is unclear. A membrane-based estrogen receptor, ER-α36, has been identified. Postmenopausal-levels of E2 act through ER-α36 to induce osteoclast apoptosis due to a prolon...

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Detalles Bibliográficos
Autores principales: Zou, Wei, Fang, Chen, Ji, Xiaofei, Liang, Xiaofeng, Liu, Yang, Han, Chao, Huang, Liang, Zhang, Qiqi, Li, Hongyan, Zhang, Yejun, Liu, Jinqiu, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618921/
https://www.ncbi.nlm.nih.gov/pubmed/26484775
http://dx.doi.org/10.1371/journal.pone.0140660