Mitochondrial DNA Depletion Reduces PARP-1 Levels and Promotes Progression of the Neoplastic Phenotype in Prostate Carcinoma

Mitochondrial dysfunction resulting from mitochondrial DNA (mtDNA) mutations and/or depletion has been correlated with cancer progression and drug resistance. To investigate the role of mtDNA in prostate cancer progression, we used LNCaP and PC-3 prostate carcinoma cells as experimental model. Compa...

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Detalles Bibliográficos
Autores principales: Moro, Loredana, Arbini, Arnaldo A., Marra, Ersilia, Greco, Margherita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2008
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618976/
https://www.ncbi.nlm.nih.gov/pubmed/18607066
http://dx.doi.org/10.3233/CLO-2008-0427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618976/
https://www.ncbi.nlm.nih.gov/pubmed/18607066
http://dx.doi.org/10.3233/CLO-2008-0427

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