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MicroRNA-17-5p induces drug resistance and invasion of ovarian carcinoma cells by targeting PTEN signaling

BACKGROUND: The miR-17-5p was overexpressed in ovarian cancer cells, and those cells were treated with paclitaxel. The proliferation of ovarian cancer cells was assessed by MTT assay. The Caspase-Glo3/7 and TUNEL assay were used to examine the effect of miR-17-5p on paclitaxel-induced apoptosis in o...

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Detalles Bibliográficos
Autores principales: Fang, Ying, Xu, Changyan, Fu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619013/
https://www.ncbi.nlm.nih.gov/pubmed/26500892
http://dx.doi.org/10.1186/s40709-015-0035-2