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Bevacizumab and Combination Chemotherapy in rectal cancer Until Surgery (BACCHUS): a phase II, multicentre, open-label, randomised study of neoadjuvant chemotherapy alone in patients with high-risk cancer of the rectum

BACKGROUND: In locally advanced rectal cancer (LARC) preoperative chemoradiation (CRT) is the standard of care, but the risk of local recurrence is low with good quality total mesorectal excision (TME), although many still develop metastatic disease. Current challenges in treating rectal cancer incl...

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Detalles Bibliográficos
Autores principales: Glynne-Jones, R., Hava, N., Goh, V., Bosompem, S., Bridgewater, J., Chau, I., Gaya, A., Wasan, H., Moran, B., Melcher, L., MacDonald, A., Osborne, M., Beare, S., Jitlal, M., Lopes, A., Hall, M., West, N., Quirke, P., Wong, Wai-Lup, Harrison, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619031/
https://www.ncbi.nlm.nih.gov/pubmed/26493588
http://dx.doi.org/10.1186/s12885-015-1764-1