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PI3K-AKT-mTOR Pathway is Dominant over Androgen Receptor Signaling in Prostate Cancer Cells

Background: Androgen receptor (AR) and the phosphatidylinositol-3 kinase (PI3K) signaling are two of the most important pathways implicated in prostate cancer. Previous work has shown that there is crosstalk between these two pathways; however, there are conflicting findings and the molecular mechan...

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Detalles Bibliográficos
Autores principales: Kaarbø, Mari, Mikkelsen, Øyvind Løveseter, Malerød, Lene, Qu, Su, Lobert, Viola H., Akgul, Gulcan, Halvorsen, Thomas, Mælandsmo, Gunhild M., Saatcioglu, Fahri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619056/
https://www.ncbi.nlm.nih.gov/pubmed/20203370
http://dx.doi.org/10.3233/CLO-2009-0487