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Promoter-like epigenetic signatures in exons displaying cell type-specific splicing

BACKGROUND: Pre-mRNA splicing occurs mainly co-transcriptionally, and both nucleosome density and histone modifications have been proposed to play a role in splice site recognition and regulation. However, the extent and mechanisms behind this interplay remain poorly understood. RESULTS: We use tran...

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Detalles Bibliográficos
Autores principales: Curado, Joao, Iannone, Camilla, Tilgner, Hagen, Valcárcel, Juan, Guigó, Roderic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619081/
https://www.ncbi.nlm.nih.gov/pubmed/26498677
http://dx.doi.org/10.1186/s13059-015-0797-8