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Cyclo-Oxygenase 2 Modulates Chemoresistance in Breast Cancer Cells Involving NF-κB

Background: Breast cancer cells can develop chemoresistance after prolonged exposure to cytotoxic drugs due to expression of the multi drug resistance (MDR) 1 gene. Type 2 cyclo-oxygenase (COX-2) inhibitors reverse the chemoresistance phenotype of a medullary thyroid carcinoma cell line, TT, and of...

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Detalles Bibliográficos
Autores principales: Zatelli, Maria Chiara, Molè, Daniela, Tagliati, Federico, Minoia, Mariella, Ambrosio, Maria Rosaria, Uberti, Ettore Degli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619115/
https://www.ncbi.nlm.nih.gov/pubmed/19940361
http://dx.doi.org/10.3233/CLO-2009-0490