Three-Dimensional Microfluidic Tri-Culture Model of the Bone Marrow Microenvironment for Study of Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) initiates and progresses in the bone marrow, and as such, the marrow microenvironment is a critical regulatory component in development of this cancer. However, ALL studies were conducted mainly on flat plastic substrates, which do not recapitulate the characterist...

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Detalles Bibliográficos
Autores principales: Bruce, Allison, Evans, Rebecca, Mezan, Ryan, Shi, Lin, Moses, Blake S., Martin, Karen H., Gibson, Laura F., Yang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619215/
https://www.ncbi.nlm.nih.gov/pubmed/26488876
http://dx.doi.org/10.1371/journal.pone.0140506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619215/
https://www.ncbi.nlm.nih.gov/pubmed/26488876
http://dx.doi.org/10.1371/journal.pone.0140506

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