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Iterative reconstruction of three-dimensional models of human chromosomes from chromosomal contact data

BACKGROUND: The entire collection of genetic information resides within the chromosomes, which themselves reside within almost every cell nucleus of eukaryotic organisms. Each individual chromosome is found to have its own preferred three-dimensional (3D) structure independent of the other chromosom...

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Detalles Bibliográficos
Autores principales: Nowotny, Jackson, Ahmed, Sharif, Xu, Lingfei, Oluwadare, Oluwatosin, Chen, Hannah, Hensley, Noelan, Trieu, Tuan, Cao, Renzhi, Cheng, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619219/
https://www.ncbi.nlm.nih.gov/pubmed/26493399
http://dx.doi.org/10.1186/s12859-015-0772-0