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Iterative reconstruction of three-dimensional models of human chromosomes from chromosomal contact data
BACKGROUND: The entire collection of genetic information resides within the chromosomes, which themselves reside within almost every cell nucleus of eukaryotic organisms. Each individual chromosome is found to have its own preferred three-dimensional (3D) structure independent of the other chromosom...
Autores principales: | Nowotny, Jackson, Ahmed, Sharif, Xu, Lingfei, Oluwadare, Oluwatosin, Chen, Hannah, Hensley, Noelan, Trieu, Tuan, Cao, Renzhi, Cheng, Jianlin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619219/ https://www.ncbi.nlm.nih.gov/pubmed/26493399 http://dx.doi.org/10.1186/s12859-015-0772-0 |
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