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Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total mesorectal excision or nonoperative management

BACKGROUND: Treatment of patients with non-metastatic, locally advanced rectal cancer (LARC) includes pre-operative chemoradiation, total mesorectal excision (TME) and post-operative adjuvant chemotherapy. This trimodality treatment provides local tumor control in most patients; but almost one-third...

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Detalles Bibliográficos
Autores principales: Smith, J. Joshua, Chow, Oliver S., Gollub, Marc J., Nash, Garrett M., Temple, Larissa K., Weiser, Martin R., Guillem, José G., Paty, Philip B., Avila, Karin, Garcia-Aguilar, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619249/
https://www.ncbi.nlm.nih.gov/pubmed/26497495
http://dx.doi.org/10.1186/s12885-015-1632-z