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Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total mesorectal excision or nonoperative management
BACKGROUND: Treatment of patients with non-metastatic, locally advanced rectal cancer (LARC) includes pre-operative chemoradiation, total mesorectal excision (TME) and post-operative adjuvant chemotherapy. This trimodality treatment provides local tumor control in most patients; but almost one-third...
Autores principales: | Smith, J. Joshua, Chow, Oliver S., Gollub, Marc J., Nash, Garrett M., Temple, Larissa K., Weiser, Martin R., Guillem, José G., Paty, Philip B., Avila, Karin, Garcia-Aguilar, Julio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619249/ https://www.ncbi.nlm.nih.gov/pubmed/26497495 http://dx.doi.org/10.1186/s12885-015-1632-z |
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