AlloPred: prediction of allosteric pockets on proteins using normal mode perturbation analysis

BACKGROUND: Despite being hugely important in biological processes, allostery is poorly understood and no universal mechanism has been discovered. Allosteric drugs are a largely unexplored prospect with many potential advantages over orthosteric drugs. Computational methods to predict allosteric sit...

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Detalles Bibliográficos
Autores principales: Greener, Joe G, Sternberg, Michael JE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619270/
https://www.ncbi.nlm.nih.gov/pubmed/26493317
http://dx.doi.org/10.1186/s12859-015-0771-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619270/
https://www.ncbi.nlm.nih.gov/pubmed/26493317
http://dx.doi.org/10.1186/s12859-015-0771-1

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