Loss of CDC4/FBXW7 in Gastric Carinoma

Background: CDC4/FBXW7, encoding a ubiquitin ligase, maps to 4q32 and has been implicated as a tumor suppressor gene and therapeutic target in many tumor types. Mutations in colonic adenomas, and the frequent losses on 4q described in gastric cancer prompt speculation about the role of CDC4/FBXW7 in...

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Detalles Bibliográficos
Autores principales: Milne, A. N., Leguit, R., Corver, W. E., Morsink, F. H. M., Polak, M., de Leng, W. W., Carvalho, R., Offerhaus, G. J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2010
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619292/
https://www.ncbi.nlm.nih.gov/pubmed/20448329
http://dx.doi.org/10.3233/CLO-2010-523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619292/
https://www.ncbi.nlm.nih.gov/pubmed/20448329
http://dx.doi.org/10.3233/CLO-2010-523

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