Model-based adaptive phase I trial design of post-transplant decitabine maintenance in myelodysplastic syndrome

BACKGROUND: This report focuses on the adaptive phase I trial design aimed to find the clinically applicable dose for decitabine maintenance treatment after allogeneic hematopoietic stem cell transplantation in patients with higher-risk myelodysplastic syndrome and secondary acute myeloid leukemia....

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Detalles Bibliográficos
Autores principales: Han, Seunghoon, Kim, Yoo-Jin, Lee, Jongtae, Jeon, Sangil, Hong, Taegon, Park, Gab-jin, Yoon, Jae-Ho, Yahng, Seung-Ah, Shin, Seung-Hwan, Lee, Sung-Eun, Eom, Ki-Seong, Kim, Hee-Je, Min, Chang-Ki, Lee, Seok, Yim, Dong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619308/
https://www.ncbi.nlm.nih.gov/pubmed/26497198
http://dx.doi.org/10.1186/s13045-015-0208-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619308/
https://www.ncbi.nlm.nih.gov/pubmed/26497198
http://dx.doi.org/10.1186/s13045-015-0208-3

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