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Whole genome sequencing reveals genomic heterogeneity and antibiotic purification in Mycobacterium tuberculosis isolates

BACKGROUND: Whole genome sequencing has revolutionised the interrogation of mycobacterial genomes. Recent studies have reported conflicting findings on the genomic stability of Mycobacterium tuberculosis during the evolution of drug resistance. In an age where whole genome sequencing is increasingly...

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Detalles Bibliográficos
Autores principales: Black, PA, de Vos, M., Louw, GE, van der Merwe, RG, Dippenaar, A., Streicher, EM, Abdallah, AM, Sampson, SL, Victor, TC, Dolby, T., Simpson, JA, van Helden, PD, Warren, RM, Pain, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619333/
https://www.ncbi.nlm.nih.gov/pubmed/26496891
http://dx.doi.org/10.1186/s12864-015-2067-2