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Whole genome sequencing reveals genomic heterogeneity and antibiotic purification in Mycobacterium tuberculosis isolates
BACKGROUND: Whole genome sequencing has revolutionised the interrogation of mycobacterial genomes. Recent studies have reported conflicting findings on the genomic stability of Mycobacterium tuberculosis during the evolution of drug resistance. In an age where whole genome sequencing is increasingly...
Autores principales: | Black, PA, de Vos, M., Louw, GE, van der Merwe, RG, Dippenaar, A., Streicher, EM, Abdallah, AM, Sampson, SL, Victor, TC, Dolby, T., Simpson, JA, van Helden, PD, Warren, RM, Pain, A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619333/ https://www.ncbi.nlm.nih.gov/pubmed/26496891 http://dx.doi.org/10.1186/s12864-015-2067-2 |
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