Leveraging local ancestry to detect gene-gene interactions in genome-wide data

BACKGROUND: Although genome-wide association studies have successfully identified thousands of variants associated to complex traits, these variants only explain a small amount of the entire heritability of the trait. Gene-gene interactions have been proposed as a source to explain a significant per...

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Detalles Bibliográficos
Autores principales: Aschard, Hugues, Gusev, Alexander, Brown, Robert, Pasaniuc, Bogdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619349/
https://www.ncbi.nlm.nih.gov/pubmed/26498930
http://dx.doi.org/10.1186/s12863-015-0283-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619349/
https://www.ncbi.nlm.nih.gov/pubmed/26498930
http://dx.doi.org/10.1186/s12863-015-0283-z

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