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Leveraging local ancestry to detect gene-gene interactions in genome-wide data
BACKGROUND: Although genome-wide association studies have successfully identified thousands of variants associated to complex traits, these variants only explain a small amount of the entire heritability of the trait. Gene-gene interactions have been proposed as a source to explain a significant per...
Autores principales: | Aschard, Hugues, Gusev, Alexander, Brown, Robert, Pasaniuc, Bogdan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619349/ https://www.ncbi.nlm.nih.gov/pubmed/26498930 http://dx.doi.org/10.1186/s12863-015-0283-z |
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