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In Vitro Generation of Functional Liver Organoid-Like Structures Using Adult Human Cells

In this study we used differentiated adult human upcyte(®) cells for the in vitro generation of liver organoids. Upcyte(®) cells are genetically engineered cell strains derived from primary human cells by lenti-viral transduction of genes or gene combinations inducing transient proliferation capacit...

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Detalles Bibliográficos
Autores principales: Ramachandran, Sarada Devi, Schirmer, Katharina, Münst, Bernhard, Heinz, Stefan, Ghafoory, Shahrouz, Wölfl, Stefan, Simon-Keller, Katja, Marx, Alexander, Øie, Cristina Ionica, Ebert, Matthias P., Walles, Heike, Braspenning, Joris, Breitkopf-Heinlein, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619350/
https://www.ncbi.nlm.nih.gov/pubmed/26488607
http://dx.doi.org/10.1371/journal.pone.0139345