Small PARP inhibitor PJ-34 induces cell cycle arrest and apoptosis of adult T-cell leukemia cells

BACKGROUND: HTLV-I is associated with the development of an aggressive form of lymphocytic leukemia known as adult T-cell leukemia/lymphoma (ATLL). A major obstacle for effective treatment of ATLL resides in the genetic diversity of tumor cells and their ability to acquire resistance to chemotherapy...

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Detalles Bibliográficos
Autores principales: Bai, Xue Tao, Moles, Ramona, Chaib-Mezrag, Hassiba, Nicot, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619390/
https://www.ncbi.nlm.nih.gov/pubmed/26497583
http://dx.doi.org/10.1186/s13045-015-0217-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619390/
https://www.ncbi.nlm.nih.gov/pubmed/26497583
http://dx.doi.org/10.1186/s13045-015-0217-2

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