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Identification of Critical Amino Acids Conferring Lethality in VopK, a Type III Effector Protein of Vibrio cholerae: Lessons from Yeast Model System

VopK, a type III effector protein, has been implicated in the pathogenesis of Vibrio cholerae strains belonging to diverse serogroups. Ectopic expression of this protein exhibits strong toxicity in yeast model system. In order to map critical residues in VopK, we scanned the primary sequence guided...

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Detalles Bibliográficos
Autores principales: Bankapalli, Leela Krishna, Mishra, Rahul Chandra, Singh, Balvinder, Raychaudhuri, Saumya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619451/
https://www.ncbi.nlm.nih.gov/pubmed/26488395
http://dx.doi.org/10.1371/journal.pone.0141038