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Identification of Critical Amino Acids Conferring Lethality in VopK, a Type III Effector Protein of Vibrio cholerae: Lessons from Yeast Model System
VopK, a type III effector protein, has been implicated in the pathogenesis of Vibrio cholerae strains belonging to diverse serogroups. Ectopic expression of this protein exhibits strong toxicity in yeast model system. In order to map critical residues in VopK, we scanned the primary sequence guided...
Autores principales: | Bankapalli, Leela Krishna, Mishra, Rahul Chandra, Singh, Balvinder, Raychaudhuri, Saumya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619451/ https://www.ncbi.nlm.nih.gov/pubmed/26488395 http://dx.doi.org/10.1371/journal.pone.0141038 |
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