Target prediction utilising negative bioactivity data covering large chemical space

BACKGROUND: In silico analyses are increasingly being used to support mode-of-action investigations; however many such approaches do not utilise the large amounts of inactive data held in chemogenomic repositories. The objective of this work is concerned with the integration of such bioactivity data...

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Detalles Bibliográficos
Autores principales: Mervin, Lewis H., Afzal, Avid M., Drakakis, Georgios, Lewis, Richard, Engkvist, Ola, Bender, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619454/
https://www.ncbi.nlm.nih.gov/pubmed/26500705
http://dx.doi.org/10.1186/s13321-015-0098-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619454/
https://www.ncbi.nlm.nih.gov/pubmed/26500705
http://dx.doi.org/10.1186/s13321-015-0098-y

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