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Association of activated Gα(q) to the tumor suppressor Fhit is enhanced by phospholipase Cβ
BACKGROUND: G proteins are known to modulate various growth signals and are implicated in the regulation of tumorigenesis. The tumor suppressor Fhit is a newly identified interaction partner of G(q) proteins that typically stimulate the phospholipase C pathway. Activated Gα(q) subunits have been sho...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619496/ https://www.ncbi.nlm.nih.gov/pubmed/26497576 http://dx.doi.org/10.1186/s12885-015-1802-z |