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Inhibition of Matriptase Activity Results in Decreased Intestinal Epithelial Monolayer Integrity In Vitro
Barrier dysfunction in inflammatory bowel diseases implies enhanced paracellular flux and lowered transepithelial electrical resistance (TER) causing effective invasion of enteropathogens or altered intestinal absorption of toxins and drug compounds. To elucidate the role of matriptase-driven cell s...
Autores principales: | Pászti-Gere, E., McManus, S., Meggyesházi, N., Balla, P., Gálfi, P., Steinmetzer, T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619522/ https://www.ncbi.nlm.nih.gov/pubmed/26488575 http://dx.doi.org/10.1371/journal.pone.0141077 |
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