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Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer

BACKGROUND: Understanding cell signaling pathways that contribute to metastatic colon cancer is critical to risk stratification in the era of personalized therapeutics. Here, we dissect the unique involvement of mitogenic pathways in a TGFβ or activin-induced metastatic phenotype of colon cancer. ME...

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Detalles Bibliográficos
Autores principales: Bauer, Jessica, Ozden, Ozkan, Akagi, Naomi, Carroll, Timothy, Principe, Daniel R., Staudacher, Jonas J., Spehlmann, Martina E., Eckmann, Lars, Grippo, Paul J., Jung, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619565/
https://www.ncbi.nlm.nih.gov/pubmed/26497569
http://dx.doi.org/10.1186/s12943-015-0456-4