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Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer
BACKGROUND: Understanding cell signaling pathways that contribute to metastatic colon cancer is critical to risk stratification in the era of personalized therapeutics. Here, we dissect the unique involvement of mitogenic pathways in a TGFβ or activin-induced metastatic phenotype of colon cancer. ME...
Autores principales: | Bauer, Jessica, Ozden, Ozkan, Akagi, Naomi, Carroll, Timothy, Principe, Daniel R., Staudacher, Jonas J., Spehlmann, Martina E., Eckmann, Lars, Grippo, Paul J., Jung, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619565/ https://www.ncbi.nlm.nih.gov/pubmed/26497569 http://dx.doi.org/10.1186/s12943-015-0456-4 |
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