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Depletion of M. tuberculosis GlmU from Infected Murine Lungs Effects the Clearance of the Pathogen
M. tuberculosis N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU(Mtb)) is a bi-functional enzyme engaged in the synthesis of two metabolic intermediates N-acetylglucosamine-1-phosphate (GlcNAc-1-P) and UDP-GlcNAc, catalyzed by the C- and N-terminal domains respectively. UDP-GlcNAc is a key m...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619583/ https://www.ncbi.nlm.nih.gov/pubmed/26489015 http://dx.doi.org/10.1371/journal.ppat.1005235 |