Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells

We demonstrated for the first time an outstanding ability of rosiglitazone to mediate a profound enhancement of LA-12-induced apoptosis associated with activation of mitochondrial pathway in human colon cancer cells. This effect was preferentially observed in the G1 cell cycle phase, independent on...

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Detalles Bibliográficos
Autores principales: Lauková, Jarmila, Kozubík, Alois, Hofmanová, Jiřina, Nekvindová, Jana, Sova, Petr, Moyer, Mary Pat, Ehrmann, Jiří, Hyršlová Vaculová, Alena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619604/
https://www.ncbi.nlm.nih.gov/pubmed/26492315
http://dx.doi.org/10.1371/journal.pone.0141020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619604/
https://www.ncbi.nlm.nih.gov/pubmed/26492315
http://dx.doi.org/10.1371/journal.pone.0141020

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