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Functional Impairment of Myeloid Dendritic Cells during Advanced Stage of HIV-1 Infection: Role of Factors Regulating Cytokine Signaling

INTRODUCTION: Severely immunocompromised state during advanced stage of HIV-1 infection has been linked to functionally defective antigen presentation by dendritic cells (DCs). The molecular mechanisms behind DC impairment are still obscure. We investigated changes in DC function and association of...

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Detalles Bibliográficos
Autores principales: Sachdeva, Meenakshi, Sharma, Aman, Arora, Sunil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619614/
https://www.ncbi.nlm.nih.gov/pubmed/26492336
http://dx.doi.org/10.1371/journal.pone.0140852